The Ss. Cyril and Methodius University's mission is to be:
an autonomous, scientific and higher educational university which provides teaching, scholar and applied activities in technical, natural sciences and mathematics, bio-technical, artistic, medical and social sciences;
a university dedicated to the cherishing as well as international recognition of the traditional features and values the Macedonian people (the Macedonian language, history, literature and culture) and at the same time to the nurturing of the cultural values of the other ethnic communities in the Republic of Macedonia;
a university open to all students on the basis of equality and their academic results regardless of their ideological, political, cultural and social origin;
a university that coordinates its academic offer to the needs of the social surrounding, and has continuously dynamic relation towards it;
a university that creates stimulative environment for its employees, providing them a progress of their abilities in order to accomplish its mission;
a university which develops long-life and continuing education;
a university determined to achieve the European norms and standards in all spheres of its activities.